Analysis of Biological Networks, Spring 2023
0368-4212-01

 

Instructor: Roded Sharan
Time: Monday 13-16


Syllabus and Handouts

The syllabus for the course is here

Following is a tentative outline of the course, which will be updated according to what is actually studied in class:

 

Week

Date

Lecture scribes

Read more

(refs. are below)

1

20 Mar

Introduction to cell biology and networks

Molecular biology of the cell, Alberts et al.

2

27 Mar

Network measures and random network models

Reviews/Tutorials

3

17 Apr

Protein-protein interaction networks : data processing & functional annotation

4

24 Apr

Integer linear programming

5

1 May

Network modules

6

8 May

More on Network modules 

*

7

15 May

Local network alignment; Global network alignment

8

22 May

Network querying

9

29 May

Functional subnetwork inference

*

10

5 Jun

Network orientation and signing

11

12 Jun

Boolean network modeling

12

19 Jun

Networks in disease; Network integration

13

26 Jun

Project presentations

 

Reviews/tutorials on Biological Networks

1.      A.-L. Barabsi and Z.N. Oltvai. Network biology: understanding the cell's functional organization. Nat. Rev. Genet. 5:101-113, 2004.

2.      M.E.J. Newman. The structure and function of complex networks. SIAM Reviews 45:167-256, 2003.

3.      R. Albert and A.-L. Barabasi. Statistical mechanics of complex networks. Rev. Modern Phys. 74:47-97, 2002.