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The Human Genome Project

The human genome project is a worldwide endeavor aimed to sequence the entire \( 3\times 10^{9} \)bp-long human DNA. The project, initiated by the United States in the late 80' was launched in 1990 and was intended to be completed in 15 years with a 3 billion dollar budget. The human genome project was entitled 'biology's space conquest', although its effects and benefits to biological and medical science will probably be much more significant and far reaching. More than \( 90\% \) of the human genome was sequenced so far within this project, and around \( 25\%
\) of it is defined finished, namely assembled into long pieces and reviewed.

In mid 1998, a company called Celera was initiated, announcing on its intentions to sequence the whole human genome in parallel to the public human genome project, and in shorter time. Today they claim to have the whole genome sequenced, except for holes which do not contain genes. Another company called Incyte claims to have a database of all the human genes, without the nongenic DNA.

Apart from the human genome there are some fully sequenced genomes available at public domains. Among these are the genomes of the nematode worm Caenorhabditis elegans, and the fruit fly Drosophila melanogaster, both around 108bp.

The human genome is not the only large genome which is currently being sequenced: other genomes such as the mouse and the rice genomes are also being sequenced by Celera and by public initiatives.


next up previous
Next: Bibliography Up: No Title Previous: Cloning
Peer Itsik
2000-11-13