Next: Motivation
Up: Pairwise Alignment
Previous: Motivation
Gap Penalty
Up until now the central elements used to measure the score of an alignment have been matches, mismatches and spaces. Now we introduce another important element, gaps. Gaps help create
alignments that better conform to underlying biological models and more closely fit
patterns that one expects to find in meaningful alignments. The
idea is to take in account the number of contiguous gaps and not only the
number of spaces when calculating an alignment mark This section
presents a gap penalty model for evaluating the weight of a
sequence of consecutive indel operations. The model states that
consecutive indel operations have different total weight than
simply the sum of their weights.
63#63
64#64
65#65
Peer Itsik
2000-11-20