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Eukaryote gene structure
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Promoter variation
Gene Finding in Eukaryotes
Eukaryote gene structure
Typical figures:
vertebrates
Markov Sequence Models
Splice junctions
Length Distribution
A possible Hidden Markov Model (HMM)
Exon Length Distribution
Generalized HMM
Introduction to GHMM
GenScan Model
prediction
GENSCAN
C+G Content
Initial state probabilities
Transition probabilities
State length distributions
Signal models
Performance of GENSCAN
Spliced Alignment
Definition of the spliced alignment problem
Network formulation
Spliced alignment algorithm
Improved spliced alignment algorithm
Results
Peer Itsik
2000-12-25
