Tissue Gene Expression Data

The gene expression data used in this experiment is from [7]. The authors describe an analysis of gene expression data obtained form 40 tumor and 22 normal colon tissues.

Gene expression patterns were measured for 2000 genes in 62 tissues. The similarity was measured with Pearson correlation.

BioClust formed 6 clusters. Figure 12.9 shows the distribution of tumor and normal tissues in the six clusters produced.

The main goal of clustering here is to achieve a separation of tumor and normal tissues. This experiment demonstrates the usefulness of clustering techniques in learning more about the relationship of expression profiles to tissue types.

  

Figure 12.9: Distribution of tumor and normal tissues in the six clusters produced by the algorithm.