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Structural Genomics Project
Protein Structural Alignment - The Rigid Case
Figure:
Output of the matching program [
4
]
Protein Shape Representation
Problem Definition
Advantages of the Sequence Independent Alignment
Advantages of the Sequence Dependent Approach
Analogy with Object Recognition in Computer Vision
Superposition - best least squares (RMSD) rigid alignment
Solving the Correspondence (Matching) Problem
Straightforward Algorithm
Geometric Hashing techinque based Alignment Algorithm
Geometric Hashing Technique
Alignment Algorithm
Complexity
The Flexible case
Motivation
Peer Itsik
2001-03-04