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Motivation
In many biological applications local
similarity is far more meaningful than global similarity. This is
particularly true when long stretches of non-coding DNA are
compared, since only small regions within those strings may be
related. When comparing protein sequences, local alignment is also
critical because proteins from very different families often share
the same structural or functional subunits, and local alignment is
an appropriate tool for searching such moduls.
Itshack Pe`er
1999-01-03